Diagnostic Accuracy of Behavioral, Activity, Ferritin, and Clinical Indicators of Restless Legs Syndrome
نویسندگان
چکیده
منابع مشابه
CLINICAL REVIEW Restless Legs Syndrome
Background: Restless legs syndrome is a common but not well-recognized central nervous system disorder that leads to insomnia and daytime distress. Methods: A MEDLINE search of the recent English language literature was undertaken with review of appropriate articles and references. Results: A growing body of work has added to an understanding of the epidemiology, diagnostic criteria, appropriat...
متن کاملCSF iron, ferritin and transferrin levels in restless legs syndrome.
The aim of this study is evaluating iron, ferritin, and transferrin in both serum and CSF in patients of restless legs syndrome (RLS), based on the hypothesis that iron deficiency in the central nervous system (CNS) causes the symptoms as a result of the dysfunction of dopaminergic systems. These parameters, polysomnographic sleep measures, and subjective evaluation of the sleep quality were co...
متن کاملMitochondrial ferritin in the substantia nigra in restless legs syndrome.
Restless legs syndrome (RLS) is a neurological disorder that is thought to involve decreased iron availability in the brain. Iron is required for oxidative metabolism and plays a critical role in redox reactions in mitochondria. The recent discovery of mitochondrial ferritin (FtMt) provided the opportunity to identify a potential correlation between iron and mitochondrial function in RLS. Human...
متن کاملThe restless legs syndrome.
The first description of the restless legs syndrome (RLS) is attributed to Thomas Willis in the 'London Practice of Physick' of 1685 (Ekbom, 1960). Here he wrote 'wherefore to some, when being a bed they betake themselves to sleep, presently in the arms and leggs, leapings and contractions of their tendons, and so great a restlessness and tossings of their members ensue, that the diseased are n...
متن کاملRestless legs syndrome.
Restless legs syndrome is common; it is characterised by an urge to move and usually, but not exclusively, affects the legs. This urge to move is typically accompanied by abnormal sensations, variably described as burning, tingling, aching, or “insects crawling under the skin.” These sensations are transiently or partially relieved by movement, and there is a strong circadian influence—symptoms...
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ژورنال
عنوان ژورنال: Sleep
سال: 2015
ISSN: 0161-8105,1550-9109
DOI: 10.5665/sleep.4492